Gregorios 141 was hegoumenos of an unknown monastery, he was the addressee of two surviving letters from Theodoros 15 (Theodore the Stoudite), probably both written between 821 and 826; both are letters of dogmatic instruction: Theod. Stud., Ep. 61, pp. 172-173 (containing advice on the functions of a hegoumenos; he is addressed as ὦ τέκνον: p. 173, line 14); 64, pp. 176-178. Gregorios 141 may be identical with the hegoumenos Gregorios whose unnamed oikonomos was arrested with other of his monks during the persecution under Leo V (Leo 15): Theod. Stud., Catech. Parva 14 (p. 52 Auvray).

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